• The leading primary sites of metastatic tumors to the spine in order of frequency are lung, breast and prostate
  • Spinal metastases can be either epidural, producing spinal cord compression, or, more rarely, intramedullary. The latter occurs with advanced metastatic disease and is associated with a very poor prognosis.

 

  • Gross pathology: metastatic glioblastoma (below)

  • Medulloblastoma; drip metastases from a cerebellar tumour flow down through subarachnoid space via CSF. These can encase lower spinal cord (left: gross pathology; right: CT of lumbar spine)

  • MRI images of metastatic lesions to the spinal cord (below)